Friday 10 April 2020

Documentary: The Crisis of Science (The Corbett Report)



In 2015 a study from the Institute of Diet and Health with some surprising results launched a slew of click bait articles with explosive headlines: “Chocolate accelerates weight loss” insisted one such headline.

“Scientists say eating chocolate can help you lose weight” declared another.

“Lose 10% More Weight By Eating A Chocolate Bar Every Day…No Joke!” promised yet another.

There was just one problem: This was a joke.

The head researcher of the study, “Johannes Bohannon,” took to io9 in May of that year to reveal that his name was actually John Bohannon, the “Institute of Diet and Health” was in fact nothing more than a website, and the study showing the magical weight loss effects of chocolate consumption was bogus. The hoax was the brainchild of a German television reporter who wanted to “demonstrate just how easy it is to turn bad science into the big headlines behind diet fads.”

Given how widely the study’s surprising conclusion was publicized—from the pages of Bild, Europe’s largest daily newspaper to the TV sets of viewers in Texas and Australia—that demonstration was remarkably successful. But although it’s tempting to write this story off as a demonstration about gullible journalists and the scientific illiteracy of the press, the hoax serves as a window into a much larger, much more troubling story.

That story is The Crisis of Science. This is The Corbett Report.

What makes the chocolate weight loss study so revealing isn’t that it was completely fake; it’s that in an important sense it wasn’t fake. Bohannes really did conduct a weight loss study and the data really does support the conclusion that subjects who ate chocolate on a low-carb diet lose weight faster than those on a non-chocolate diet. In fact, the chocolate dieters even had better cholesterol readings. The trick was all in how the data was interpreted and reported.

As Bohannes explained in his post-hoax confession:

“Here’s a dirty little science secret: If you measure a large number of things about a small number of people, you are almost guaranteed to get a ‘statistically significant’ result. Our study included 18 different measurements—weight, cholesterol, sodium, blood protein levels, sleep quality, well-being, etc.—from 15 people. (One subject was dropped.) That study design is a recipe for false positives.”

You see, finding a “statistically significant result” sounds impressive and helps scientists to get their paper published in high-impact journals, but “statistical significance” is in fact easy to fake. If, like Bohannes, you use a small sample size and measure for 18 different variables, it’s almost impossible not to find some “statistically significant” result. Scientists know this, and the process of sifting through data to find “statistically significant” (but ultimately meaningless) results is so common that it has its own name: “p-hacking” or “data dredging.”

But p-hacking only scrapes the surface of the problem. From confounding factors to normalcy bias to publication pressures to outright fraud, the once-pristine image of science and scientists as an impartial font of knowledge about the world has been seriously undermined over the past decade.

Although these types of problems are by no means new, they came into vogue when John Ioannidis, a physician, researcher and writer at the Stanford Prevention Research Center, rocked the scientific community with his landmark paper “Why Most Published Research Findings Are False.” The 2005 paper addresses head on the concern that “most current published research findings are false,” asserting that “for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias.” The paper has achieved iconic status, becoming the most downloaded paper in the Public Library of Science and launching a conversation about false results, fake data, bias, manipulation and fraud in science that continues to this day.

Source: The Corbett Report

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